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The potential for testosterone transfer following administration of Testosterone Gel, 1. In one study, 8 male subjects applied a single dose of Testosterone Gel, 1. Two 2 hours after application, female subjects rubbed their hands, wrists, arms, and shoulders to the application site of the male subjects for 15 minutes. Serum concentrations of testosterone were monitored in female subjects for 24 hours after contact occurred. In a second study evaluating transfer of testosterone, 12 male subjects applied a single dose of Testosterone Gel, 1. Two 2 hours after application, female subjects rubbed their hands, wrists, arms, and shoulders to the application site of the male subjects for 15 minutes while the site of application was Test Cyp by a t-shirt. A separate study was conducted to evaluate the potential for testosterone transfer from 16 males Liquid Testosterone Cypionate with Testosterone Gel, 1. Two 2 Test C after application to the males on each day, the female subjects rubbed their abdomens for 15 minutes to the abdomen of the males, Liquid Testosterone Cypionate. The males had covered the application area with a T-shirt. In a randomized, 3-way 3 treatment periods without washout period crossover study in 24 hypogonadal men, the effect of showering on testosterone exposure was assessed after once daily application of Testosterone Gel, 1. On the 7th day of each treatment period, hypogonadal men took a shower with soap and water at either 2, 6, or 10 hours after drug application. Showering at 10 hours after drug application had no effect on bioavailability. In a randomized, open-label, single-dose, 2-way crossover study in 16 healthy male subjects, the effect of hand washing on the amount of residual testosterone on the hands was evaluated. Subjects used their hands to apply the maximum dose 81 mg testosterone of Testosterone Gel, 1.




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